S13-02 In vivo visualization of hematopoietic stem cell generation
نویسندگان
چکیده
منابع مشابه
S13-02 In vivo visualization of hematopoietic stem cell generation
The purification, renewal and differentiation of native cardiac progenitors would form a mechanistic underpinning for unraveling steps for cardiac cell lineage formation, and their links to forms of congenital and adult cardiac diseases. Previously, we have reported the identification of isl1+ cardiac progenitors in postnatal rat, mouse and human myocardium (1). The discovery of native cardiobl...
متن کاملPediatric Hematopoietic Stem Cell Transplantation
The introduction and evolution of hematopoietic stem cell transplantation (HSCT) could be traced back to 1950s, to the studies on interactions among irradiation, covering spleen and bone marrow from it and injection of bone marrow cells. Today, HSCT is considered a well-established, effective and promising means of therapy for various malignant and non-malignant medical conditions, both in chil...
متن کاملAdvances in Hematopoietic Stem Cell Mobilization and Peripheral Blood Stem Cell Transplantation
Hematopoietic stem/progenitor cells (HSPCs) which give rise to different blood cell types are present within the bone marrow microenvironment, especially in flat bones such as skull, vertebrae, pelvis and chest. Interacting factors such as stromal derived factor-1/CXCR4, very late antigen-4/vascular cell adhesion molecule-1, Lymphocyte function-associated antigen-1/ intercellular adhesion molec...
متن کاملHematopoietic Stem Cell Transplantation for Thalassemia
Thalassemia is an autosomal recessive disorder associated with defective synthesis of the α- or β-chain of hemoglobin. For β-thalassemia major patients, therapeutic options are either monthly red cell transfusions and chelation therapy or allogeneic stem cell transplant. Stem cell transplant is the only curative approach and success is inversely correlated with the degree of iron overload and h...
متن کاملS13-05 Harnessing epithelial stem cell potency
naling events that are continuously modified by environmental cues. However, the details of how these processes can change cell fate choices are still unknown. Previously, we demonstrated that sustained expression of HOXA3 both accelerated wound healing and promoted neovascularisation in diabetic mice. We have subsequently shown that in response to injury HOXA3 induces a significant increase in...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 2009
ISSN: 0925-4773
DOI: 10.1016/j.mod.2009.06.1025